Opta has made Manchester City overwhelming favourites to win the Premier League.
This follows shock defeats suffered by Liverpool and Arsenal on Sunday.
The Reds lost 1-0 to Crystal Palace, while the Gunners were beaten 2-0 at home by Aston Villa.
Following the completion of the games, Opta’s title predictor is now up to 70% in favour of Manchester City winning the Premier League.
Arsenal have an 18% chance of winning it and Liverpool a 12% chance.
The next round of games will see City away at Brighton and Arsenal travel to Wolves.
Liverpool will play Fulham at Craven Cottage.
EPL: SuperComputer predicts title winners after Arsenal, Liverpool defeats
